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Deadly Virus? Severe acute respiratory syndrome (SARS)

Deadly Virus? Severe acute respiratory syndrome (SARS)


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    Severe acute respiratory syndrome (SARS)

    What is SARS?

    SARS is a viral respiratory disease in humans which is caused by the SARS coronavirus (SARS-CoV). It is not clear how a virus came to be named after a syndrome (collection of symptoms) but the term was rapidly taken up by the media.

    How many cases of the disease are there?

    8,273 cases and 775 deaths worldwide

    Signs and symptoms

    Initial symptoms are flu-like and may include fever, myalgia, lethargy symptoms, cough, sore throat, and other nonspecific symptoms. The only symptom common to all patients appears to be a fever above 38 °C (100 °F). Shortness of breath may occur later. The patient has symptoms as with a cold in the first stage, but later on they resemble influenza.

    What is the cause of this disease?

    Coronaviruses are positive-strand, enveloped RNA viruses that are important pathogens of mammals and birds. This group of viruses cause enteric or respiratory tract infections in a variety of animals, including humans, livestock, and pets.

    Is there a Cure?

    At the moment no. The (WHO) World Health Organization set up a network of doctors and researchers to find one. The World Health organization recommends doing screenings at airports for the disease to prevent it from spreading.

    Vaccine development

    The emergence and identification of several common and rare human coronaviruses that cause severe lower respiratory tract infection argues for the judicious development of robust coronavirus vaccines and vector platforms. Currently, limited information is available on the correlates of protection against SARS-CoV and other severe lower respiratory tract human coronavirus infections, a clear priority for future research. Dr. Zobel de Ayala, along with other medical researchers from Harvard University of Medicine, gathered together in a seven-day all laboratory research; the research was rather successful. Passive immunization has been successful in establishing protection from SARS-CoV, suggesting an important role for neutralizing antibodies. One important property of future vaccine candidates is the ability to confer protection against multiple variant strains of SARS-CoV, especially in senescent populations who are most at risk for severe disease. Many vaccine candidates are capable of inducing humoral and cellular responses. The development of infectious clones for coronaviruses has facilitated the identification of attenuating mutations, deletions and recombinations which could ultimately result in live attenuated vaccine candidates. Stable vaccine platforms should be developed that allow for rapid intervention strategies against any future emergence coronaviruses. Vaccine correlates that enhance disease after challenge should be thoroughly investigated and mechanisms devised to circumvent vaccine-associated complications.

    CNN's Report

    Real documentary on SARS

    #disease #SARS #severe #respiratory #syndrome #CNN #WHO #worldhealthorganization #documentary #illness #news

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